我院遇到使用青霉素 G 钾后,更换国产氨苄青霉素发生过敏反应二例,报告如下。例1:丁××,女,36岁,住院号70967,因下腹部坠痛,伴腰痛,白带增多一周,于1979年元月12日入院。元月19日肌注青霉素 G 钾80万单位(皮试阴性),4次/日,用至元月22日,改用氨苄青霉素0.5,3日/次,未作皮试,首次注射此药,约注入1/2时,患者突然出现心慌,手脚麻木,恶心欲吐,两眼发红等过敏反应症状。此时,立即拔针,随 I met hospital use of penicillin G potassium, the replacement of domestic ampicillin allergic reaction occurred in two cases, the report is as follows. Example 1: Ding × ×, female, 36 years old, hospitalization 70967, due to lower abdomen pain, with low back pain, leucorrhea increased one week, January 12, 1979 admission. January 19, intramuscular injection of penicillin G potassium 800,000 units (skin test negative), 4 times / day, with January 22, changed to ampicillin 0.5, 3 days / times, no skin test, the first injection of the drug , About injection of 1/2, the patient suddenly appeared palpitation, numbness, nausea, redness and other allergic symptoms. At this point, immediately pull the needle, with