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目的：评价脑血流灌注显像在各种神经系统疾病中诊断价值。方法：对４７例脑外伤、脑血管病等神经系统疾病进行９９ｍＴｃ标记双半胱乙酯（９９ｍＴｃＥＣＤ）脑血流灌注断层显像，部分检查和ＣＴ进行比较。结果：１０例轻度脑外伤和４例脑挫裂伤显示局部脑血流量（ｒＣＢＦ）减少，在１５例轻度脑外伤，单光子断层成像（ＳＰＥＣＴ）和ＣＴ诊断阳性率分别为４０％和１３％；１１例脑血管病中９例显示病灶处ｒＣＢＦ减少，其中５例出现交叉性神经功能联系中断。在１１例脑血管病中ＳＰＥＣＴ和ＣＴ阳性率分别为８２％和７３％。另有老年性痴呆、癫痫和偏头痛各１例显示ｒＣＢＦ异常。结论：９９ｍＴｃＥＣＤ脑血流灌注显像对中枢神经疾病的诊断和研究有重要意义。
Objective: To evaluate the diagnostic value of cerebral perfusion imaging in various neurological diseases. Methods: Totally 47 cases of cerebral diseases such as traumatic brain injury and cerebrovascular disease were subjected to 99mTc-labeled 99mTc-ECD cerebral perfusion tomography. Some examinations were compared with CT. Results: 10 cases of mild traumatic brain injury and 4 cases of cerebral contusion and laceration showed decreased local cerebral blood flow (rCBF). The positive rates of SPECT and CT in 15 cases were 40% and 15% respectively 13%; 9 cases of 11 cases of cerebrovascular disease showed reduced rCBF lesions, of which 5 cases of intercross nerve function interruption. In 11 cases of cerebrovascular disease SPECT and CT positive rates were 82% and 73%. Another Alzheimer’s disease, epilepsy and migraine in 1 case showed rCBF abnormalities. Conclusion: 99mTc ECD cerebral perfusion imaging of central nervous system disease diagnosis and research is of great significance.