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对27例控制不良的糖尿病人(DM)及10例正常对照者测定血清铁(SI)、铁蛋白(SF)及总铁结合力(TIBC)测定。27例DM分为A、B两组,A组病程长、有慢性并发症;B组病程短、无慢性并发症。结果表明:27例DM之SF均明显高于正常对照组,而DMA组SF又明显高于DMB组(P<0.05)。DM组与正常对照组之间SI、TIBC值无明显差异。本组资料提示DM尤其是伴慢性并发症者有SF升高,表明体内铁贮存过多,此可降低葡萄糖的外周利用并损伤胰岛β细胞,故铁贮存过量可能是DM及慢性并发症发生与发展的因素之一。
Serum iron (SI), ferritin (SF) and total iron binding capacity (TIBC) were determined in 27 poorly controlled diabetic patients and 10 normal controls. 27 cases of DM were divided into A and B groups, A group of long course of disease, chronic complications; B group of short course, no chronic complications. The results showed that the SF of 27 DM patients was significantly higher than that of the normal control group, while SF of DMA group was significantly higher than that of DMB group (P <0.05). There was no significant difference in SI and TIBC between DM group and normal control group. This group of data suggest that DM, especially with chronic complications who have SF increased, indicating that excessive iron storage in the body, which can reduce peripheral glucose utilization and damage islet β cells, so iron overdose may DM and chronic complications and One of the factors of development.