寻找疟疾病因性预防药物,是疟疾防治上的一个非常关键的课题。过去寻找病因性预防药物之所以进展缓慢,主要是由于没有满意的实验动物模型。近年来,由于实验动物模型的建立和筛选方法的改进,已取得进展。Davidson为了研究组织内裂殖体杀灭剂曾从4,000个化合物的动物筛选中,发现了700多 Looking for malaria etiology preventive drugs, malaria control is a very key issue. The slow progress in finding causal agents in the past was largely due to the lack of satisfactory experimental animal models. In recent years, advances have been made due to the establishment of experimental animal models and the improvement of screening methods. Davidson has screened more than 700 animals from 4,000 compounds in order to study intraspecific schizonts.