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目的探讨仪器法和镜检法计数白血病幼稚粒细胞百分比的相关性和一致性。方法 2009年69月对71例慢性粒细胞性白血病(慢粒)、亚急性粒细胞性白血病(M2)、急性早幼粒细胞性白血病(M3)及急性粒单核细胞性白血病(M4)白血病患者进行仪器法和镜检法计数周围静脉血幼稚粒细胞的百分比的检测,并进行比较分析。结果两种方法计数的慢粒、M2、M3及M4型共71例白血病患者的幼稚粒细胞的百分比比较,有统计学意义(t=6.404,P<0.01);但具有相关性(r=0.771,P<0.001)。且四种类型白血病中的每一种类型的白血病的两种方法的幼粒值也都具有相关性和不一致性(P<0.05)。结论 SYSMEX XE-2100全自动血细胞分析仪对慢粒、M2、M3及M4的周围静脉血幼稚粒细胞识别能力欠佳,仍需采用镜检法进行检测。
Objective To explore the correlation and consistency between the instrumental method and the microscopic examination of immature granulocyte percentage of leukemia. Methods Ninety-one patients with chronic myelogenous leukemia (CML), sub-acute myelogenous leukemia (M2), acute promyelocytic leukemia (M3) and acute myelomonocytic leukemia Patients were instrumental and microscopic examination of peripheral venous blood count the percentage of immature granulocytes, and comparative analysis. Results The percentages of immature granulocytes in 71 cases of leukemia patients with M2, M3 and M4 were statistically significant (t = 6.404, P <0.01), but correlated with each other (r = 0.771 , P <0.001). And the young values of the two methods for each of the four types of leukemia were also correlated and inconsistent (P <0.05). Conclusion The SYSMEX XE-2100 automatic hematology analyzer has poor ability of recognizing immature granulocytes in peripheral blood of CML, M2, M3 and M4, and still needs to be examined by microscopic examination.