论文部分内容阅读
目的应用左室纵向应变评估射血分数正常的重度子痫前期患者左室收缩功能。方法选取重度子痫前期患者52例作为病例组,40例年龄、孕周匹配的健康孕妇作为正常组,所有入选者LVEF≥50%,产前及产后均采集二维斑点追踪技术所需相关切面图像,计算各切面左室整体纵向应变(GLS)及左室整体纵向平均应变(GLS-Avg)。结果病例组产前2C-GLS、4C-GLS、LAX-GLS、GLS-Avg均低于正常组产前(P<0.05);病例组产后2C-GLS、4CGLS、GLS-Avg均低于正常组产后(P<0.05);病例组产前2C-GLS、4C-GLS均低于病例组产后(P<0.05);正常组产前2CGLS、4C-GLS、LAX-GLS、GLS-Avg均低于正常组产后(P<0.05)。结论射血分数正常的重度子痫前期患者存在早期左室收缩功能的损害;通过二维斑点追踪技术中左室纵向应变的减低,能够识别早期左室收缩功能损害。
Objective To evaluate left ventricular systolic function in patients with severe preeclampsia using left ventricular longitudinal strain. Methods Fifty-two patients with severe preeclampsia were selected as the case group and 40 healthy pregnant women with matched age and gestational age were selected as normal group. The LVEF≥50% of all the patients were enrolled. All the relevant sections of two-dimensional speckle tracking technique Images were taken and left ventricular total longitudinal strain (GLS) and left ventricular longitudinal mean strain (GLS-Avg) were calculated for each section. Results The pre-delivery 2C-GLS, 4C-GLS, LAX-GLS and GLS-Avg were lower in the case group than in the normal group (P <0.05) (P <0.05). The pre-delivery levels of 2C-GLS and 4C-GLS were lower in the case group than those in the case group (P <0.05). The pre-delivery levels of 2CGLS, 4C-GLS, LAX-GLS and GLS- Normal group after delivery (P <0.05). Conclusions Early severe preeclampsia patients with normal ejection fraction have early impairment of left ventricular systolic function. Early reduction of left ventricular longitudinal strain in two-dimensional speckle tracking technique can identify early left ventricular systolic dysfunction.