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[目的 ] 观察壳聚糖对小鼠肠道菌群的影响。[方法 ] 取昆明种小鼠 2 0只 ,随机分为观察组和对照组 ,分别灌胃壳聚糖的冰醋酸溶液 40 0 mg/ kg· d和 0 .5 %冰醋酸 ,连续七天 ,而后检测两组肠道菌群的变化。 [结果 ] 观察组双歧杆菌、乳杆菌数量比对照组明显增多 (P<0 .0 5 ) ,大肠杆菌、肠球菌数量在两组间无明显改变。 [结论 ] 2 %的壳聚糖溶液能促进双歧杆菌、乳杆菌的增殖。
[Objective] To observe the effect of chitosan on intestinal flora in mice. [Method] Twenty Kunming mice were randomly divided into observation group and control group, which were administrated with 40 0 mg / kg · d and 0.5% acetic acid in glacial acetic acid solution respectively for 7 consecutive days Changes of intestinal flora in both groups were detected. [Result] The number of Bifidobacterium and Lactobacillus in the observation group was significantly higher than that in the control group (P <0.05). The quantity of Escherichia coli and Enterococcus did not change significantly between the two groups. [Conclusion] The 2% chitosan solution can promote the proliferation of Bifidobacterium and Lactobacillus.