论文部分内容阅读
痤疮是由多因素引起的一种慢性炎症性皮肤疾病,现在主流观点认为其发病机制主要包括遗传因素、皮脂分泌过度、毛囊皮脂腺导管角化过度、皮肤炎症反应、痤疮丙酸杆菌致病和雄激素分泌过度等.其中,痤疮丙酸杆菌作为重要的致病因素多年来被广泛关注,随着研究的深入,逐渐发现痤疮丙酸杆菌在痤疮中并非以独立的病因而存在.本文就痤疮丙酸杆菌的致病机制和最新进展做一综述,以期为痤疮的临床治疗及今后的研究方向提供科学思路.“,”Acnes is a disease caused by multiple factors,the current prevalent mechanisms contain hereditary factors,excessive sebum secretion,Hyperkeratosis of sebaceous gland duct,inlfammatory reaction of skin,propionibacterium acnes and androgen. However,Propionibacterium acnes has been regarded as one of the causes of illness in the past, it is gradually acknowledged that Propionibacterium acnes is not an independent pathogeny existing in the pathogenesis of acnes. Now this review is concerned about the pathogenesis and the development on Propionibacterium acnes so that we can ifnd a rational resolution and appropriate therapeutic schedule in the research.