继利凡诺中期妊娠鼠体内示踪研究之后,对40只孕鼠的肝脏进一步作了组织放射自显影、光镜和电镜观察.结果表明:在肝细胞内有多量放射性标记的利凡诺聚集,显示解毒性反应和可逆性的病理变化,用药后4小时出现形态改变,24小时变化最明显,分娩后一周趋向基本恢复正常。 Following the rivastigmine tracer study in mid-term pregnancy in rats, the tissues of 40 pregnant rats were further subjected to autoradiography, light and electron microscopy, and the results showed that there was a large amount of radioactively labeled rivanol in liver cells , Showing detoxification reaction and reversible pathological changes, morphological changes occurred 4 hours after treatment, the most obvious changes 24 hours a week after delivery tends to return to normal.