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目的探讨综合干预措施对合并慢性阻塞性肺部疾病(COPD)胆囊炎患者腹腔镜胆囊切除术(LC)后的肺功能影响及临床应用价值。方法筛选出中度以上COPD患者3 166例,随机分为干预组和对照组。LC术前、术后检测肺功能及动脉血气分析,并观察LC术后肺部感染的发病率。结果 (1)两组内手术前后FVC、FEV1及MVV比较,差异有统计学意义(P<0.05);两组间差值比较,差异有统计学意义(P<0.01)。(2)两组术后肺部感染率比较,差异有统计学意义(P<0.05)。结论围手术期进行综合干预,能有效改善COPD患者的肺功能,减少术后肺部感染率。
Objective To investigate the effects of comprehensive interventions on pulmonary function after laparoscopic cholecystectomy (LC) in patients with chronic obstructive pulmonary disease (COPD) cholecystitis and its clinical value. Methods A total of 3 166 COPD patients with moderate or severe COPD were randomly divided into intervention group and control group. LC preoperative and postoperative pulmonary function tests and arterial blood gas analysis, and observe the incidence of postoperative LC pulmonary infection. Results (1) There were significant differences in FVC, FEV1 and MVV between the two groups before and after surgery (P <0.05). There was significant difference between the two groups (P <0.01). (2) There were significant differences in postoperative lung infection rates between the two groups (P <0.05). Conclusion Perioperative comprehensive intervention can effectively improve the lung function of COPD patients and reduce the postoperative pulmonary infection rate.