论文部分内容阅读
外周血和卵巢静脉血取自30例各种盆腔病理手术时的绝经后妇女。年龄47～81岁、绝经1～35年。闭经并有缺乏雌激素的临床表现则诊断为绝经。30例中,卵巢正常者14例、非功能性卵巢肿瘤11例、功能性卵巢肿瘤3例、间质细胞或门细胞增生2例。取血后1小时分离血清,-20℃冷冻,测定睾酮(T)、雄烯二酮(A)、雌酮(E_1)17β-雌二醇(E_2)。统计学采用双尾非配对性T检验,P<0.05认为有显著性差异。结果显示,卵巢正常的绝经后妇女卵巢静脉和外周血T浓度梯度大于A或E_1。T和A平均分泌率分别为37和46μg/天,E_1分泌率少于1μg/天,17β-E_2约为3μg/天。患任何类型卵巢肿瘤的绝经后
Peripheral blood and ovarian venous blood were taken from 30 postmenopausal women undergoing various pelvic pathological procedures. Age 47 to 81 years, menopause 1 to 35 years. Menopause and a lack of estrogen are clinically diagnosed as menopause. Among the 30 cases, 14 were normal ovaries, 11 were non-functional ovarian tumors, 3 were functional ovarian tumors, and 2 were interstitial or portal cell hyperplasia. Serum was separated 1 hour after the blood was taken and frozen at -20 ° C. Testosterone (T), androstenedione (A) and estrone (E_1) 17β-estradiol (E_2) were measured. Statistical analysis using two-tailed non-matching T test, P <0.05 considered significant differences. The results showed that the ovarian vein and peripheral blood T concentration gradient in normal ovarian menopausal women than A or E_1. The average secretion rates of T and A were 37 and 46 μg / day respectively, the rate of E 1 secretion was less than 1 μg / day and that of 17β-E 2 was about 3 μg / day. Postmenopausal women with any type of ovarian tumor