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目的:观察单纯应用氨氯地平与氨氯地平联合血脂康降血压作用的疗效比较。方法:86例高血压患者,随机分为两组,观察组43例,口服氨氯地平5 mg,qd,血脂康胶囊2粒,po,bid;对照组43例;单纯口服氨氯地平5 mg,qd;两组疗程均为30 d,观察治疗前后血压、血脂变化。结果:观察组收缩压、舒张压、胆固醇(TC)、甘油三脂(TG)、低密度脂蛋白(LDL-C)均较对照组显著下降(P<0.05或0.01),高密度脂蛋白(HDL-C)显著升高(P<0.01),治疗过程中未见不良反应。结论:氨氯地平联合血脂康降血压作用优于单纯用氨氯地平,且具有调脂作用。
Objective: To observe the effect of simple application of amlodipine and amlodipine in combination with Xuezhikang to reduce blood pressure. Methods: A total of 86 patients with hypertension were randomly divided into two groups: 43 cases in the observation group, oral amlodipine 5 mg, qd, Xuezhikang 2 capsules, po, bid; control group, 43 cases; simple oral amlodipine 5 mg , qd; two groups of treatment were 30 d, observed before and after treatment of blood pressure, blood lipid changes. Results: The systolic blood pressure, diastolic blood pressure, cholesterol (TC), triglyceride (TG) and low density lipoprotein (LDL-C) in the observation group were significantly lower than those in the control group (P0.05 or 0.01) HDL-C) was significantly increased (P <0.01), no adverse reactions in the course of treatment. Conclusion: Amlodipine and Xuezhikang are better than amlodipine in lowering blood pressure, and have lipid-lowering effect.