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目的:探讨贝复济(碱性成纤维细胞生长因子,bFGF)与八湿膏联合治疗Ⅱ°烧伤创面的疗效和机制。方法:按可比性原则将168例早期Ⅱ°烧伤患者随机分为治疗组(用贝复济与八湿膏)86例和对照组(用石蜡油)82例,观察创面愈合时间。结果:浅Ⅱ°创面愈合时间,治疗组:8.0±0.8d,对照组:12.5±1.6d;深Ⅱ°创面,治疗组:6.5±1.75d,对照组:25.5±1.85d,统计学有显著差异。结论:贝复济与八湿膏联合治疗Ⅱ°烧伤创面能显著地缩短愈合时间。
Objective: To investigate the efficacy and mechanism of Beifuji (basic fibroblast growth factor, bFGF) combined with eight wet cream in the treatment of Ⅱ ° burn wounds. Methods: According to the principle of comparability, 168 patients with early stage Ⅱ ° burn were randomly divided into treatment group (treated with Beifuji and Yuba cream) and control group (with paraffin oil), 82 cases. The wound healing time was observed. Results: The healing time of shallow Ⅱ ° wounds was 8.0 ± 0.8 days in the treatment group and 12.5 ± 1.6 days in the control group, 6.5 ± 1.75 days in the deep Ⅱ ° wound group and 25.5 ± 1.85 days in the control group difference. CONCLUSION: The treatment of Ⅱ ° burn wounds by Beifuji and Baitui cream can shorten the healing time significantly.