子宫异位内膜的种植和发展必须依赖足够的血供,新生血管形成是子宫内膜异位症(EMs)发生的基本条件。在众多与血管生成相关的因子中,碱性成纤维细胞生长因子(bFGF)起到了关键调节因子的作用。在正常子宫内膜组织中,该因子及其受体有表达,且受卵巢激素的调节。在EMs中,该因子及其受体的异常表达与异位内膜的增殖、黏附和血管生成有一定关系。 Uterine ectopic endometrial plantation and development must rely on adequate blood supply, neovascularization is the basic conditions for the occurrence of endometriosis (EMs). Among many angiogenesis-related factors, bFGF plays a key regulatory role. In normal endometrial tissue, the factor and its receptor are expressed and regulated by ovarian hormones. In EMs, the abnormal expression of this factor and its receptor has some relationship with the proliferation, adhesion and angiogenesis of ectopic endometrium.