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甲亢的临床表现部份是由于交感神经活动亢进,β肾上腺能阻滞剂如心得安就是根据这一原理而发挥治疗作用。但心得安亦可通过改变血循环中甲状腺激素之浓度而发挥治疗作用。已有报导在应用心得安后不久,正常人及甲亢患者血清T_3均下降。心得安可能通过影响甲状腺激素在周围组织的代谢而改变血循环中甲状腺激素的浓度。最近研究证实在停用心得安后肾上腺能活性增加,这在甲亢患者特别明显,但在停用心得安后对甲状腺激素浓度的影响报导很少。本文研究了甲亢患者及正常人在心得安治疗过程中及停用后甲状腺激素之浓度。
The clinical manifestations of hyperthyroidism is partly due to hyperactivity of sympathetic activity, β adrenergic blockers such as propranolol is based on this principle and play a therapeutic role. But propofol can also play a therapeutic role by changing the concentration of thyroid hormones in the blood circulation. It has been reported in the application soon after the safety of normal and hyperthyroidism serum T_3 decreased. Adventures may change the concentration of thyroid hormones in the blood circulation by affecting the metabolism of thyroid hormones in the surrounding tissues. Recent studies have shown that increased activity of adrenal gland after withdrawal of propranolol, which is particularly evident in patients with hyperthyroidism, but little effect on thyroid hormone concentration after the withdrawal of propranolol. This article studies hyperthyroidism patients and normal people in the peace of mind treatment and disable the thyroid hormone concentration.