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目的:研究生大黄煎液与生大黄粉对小鼠泻下作用。方法:空白组小鼠用蒸馏水灌胃,实验组动物用生大黄煎液与生大黄粉灌胃,观察记录动物首次排出黑便的时间及6h内排出黑便的数量。结果:生大黄煎液与生大黄粉均能明显的缩短排便时间,增加排便数;与生大黄煎液比较,生大黄粉排便时间明显延长,排便数无明显差异。结论:生大黄粉与生大黄煎液均有泻下作用,能用于便秘、肠梗阻等的治疗,如病情较急或需要较快达到清理肠道的作用,选择生大黄煎液为好。
Objective: To investigate the role of post-graduation rhubarb decoction and rhubarb powder in the purgation of mice. Methods: Mice in the blank group were treated with distilled water. Rats in the experimental group were treated with rhubarb decoction and rhubarb powder. Animals were recorded for the first time to excrete melena and the number of excreted black stools within 6 hours. Results: Both rhubarb decoction and rhubarb powder can significantly shorten the defecation time and increase the number of defecation. Compared with the rhubarb decoction, the defecation time of the rhubarb powder was significantly prolonged, and there was no significant difference in the number of defecation. Conclusion: Both rhubarb powder and rhubarb decoction have diarrhea and can be used for the treatment of constipation, intestinal obstruction, etc. If the condition is acute or needs to be quickly cleared to clear the intestinal tract, it is better to choose rhubarb decoction.