人类于 1870年即认识到吸烟与肺病的相关性 ,但直至本世纪 70年代才真正明确吸烟与肺气肿的关系 ,80年代正式提出吸烟为 COPD的主要因素。目前 ,美国吸烟人数已经超过人口总数的 2 5 % ,140 0万人患 COPD,其中 12 5 0万人患支气管炎 ,16 5万人患肺气肿。吸烟是目前引起 COPD的 In 1870, human beings recognized the relationship between smoking and lung disease. However, it was not until 70s of the last century that the relationship between smoking and emphysema was truly clarified. In the 1980s, smoking was the main factor of COPD. At present, the number of smokers in the United States has exceeded 25% of the population and 140 million people suffer from COPD, of which 12.5 million suffer from bronchitis and 165,000 have emphysema. Smoking is the cause of COPD