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目的了解复杂型小儿高热惊厥转化为癫痫的影响因素。方法对128例复杂型小儿高热惊厥患儿的临床资料进行回顾性分析。结果 128例高热惊厥患儿中,有18.75%(24/128)发展为癫痫;32例有癫痫家族史患儿转化为癫痫10例,占31.25%,显著高于无癫痫家族病史患儿的2.08%,差异有统计学意义(P<0.05);44例有影响神经系统发育因素患儿转化为癫痫11例,占25.00%,显著高于神经系统无异常患儿的1.19%,差异有统计学意义(P<0.05);在0.5 h以内由高热转化为惊厥的患儿有13例,其中有69.23%(9/13)的患儿转化为癫痫,癫痫转化率均显著高于其余各个时间距离的患儿,差异有统计学意义(P<0.01)。结论复杂型小儿高热惊厥患儿转化为癫痫的主要影响因素为有癫痫家族病史、有影响神经系统发育因素以及高热发展为惊厥时间短。
Objective To understand the influencing factors of complex convulsions in children with epilepsy. Methods The clinical data of 128 children with complicated febrile convulsions were analyzed retrospectively. Results Of the 128 children with febrile seizures, 18.75% (24/128) developed epilepsy. Thirty-two children with family history of epilepsy were converted into epilepsy in 10 cases (31.25%), significantly higher than those in family history of absence of epilepsy %, The difference was statistically significant (P <0.05); 44 cases of children with neurodevelopmental factors into epilepsy in 11 cases, accounting for 25.00%, significantly higher than 1.19% of children with no nervous system abnormalities, the difference was statistically significant (P <0.05). Thirteen children were converted from hyperthermia to convulsion in less than 0.5 hours. Among them, 69.23% (9/13) children were converted to epilepsy, the conversion rate of epilepsy was significantly higher than the rest of the time Of children, the difference was statistically significant (P <0.01). Conclusions The main influencing factors of children with complicated convulsions in treating children with epilepsy are the family history of epilepsy, the factors influencing nervous system development and the short time of developing fever.