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流行病学和分子学证实原发性肝细胞癌(PHC)病原与慢性乙型肝炎病毒(HBV)感染有关。本文作者报道希腊 PHC 病人中 HBV 和δ肝炎病毒(HDV)感染中血清学标志和 HBV 复制水平的研究结果。1978年5月至1985年5月,对47例经组织学证实为 PHC 的希腊病人(45例男性,2例女性),测定 HBV 和 HDV 感染的血清学标志。患者平均年龄65.3岁(38～89岁)。应用放射免疫法测定乙型肝炎表面抗原(HBs-
Epidemiology and molecular evidence confirm that primary hepatocellular carcinoma (PHC) pathogens are associated with chronic hepatitis B virus (HBV) infection. The authors report the results of the serological markers and HBV replication in HBV and delta hepatitis virus (HDV) infections in patients with PHC in Greece. From May 1978 to May 1985, 47 patients with histologically confirmed PHC (45 males and 2 females) were enrolled for the determination of serological markers of HBV and HDV infection. The average patient age was 65.3 years (38-89 years). Application of radioimmunoassay for the determination of hepatitis B surface antigen (HBs-