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目的探究对肺癌骨转移疼痛患者行注射用唑来膦酸治疗的影响。方法对收治的88例肺癌骨转移疼痛患者进行分组研究,参照组行注射用帕米膦酸治疗,研究组行注射用唑来膦酸治疗。结果研究组疼痛缓解情况、一般状况与生活质量评分均明显好于参照组,差异有统计学意义(P<0.05);在不良反应方面两组间差异无统计学意义(P>0.05)。结论对肺癌骨转移疼痛患者行以注射用唑来膦酸治疗可有效缓解疼痛症状,且安全性良好。
Objective To investigate the effect of zoledronic acid for injection on patients with bone metastasis of lung cancer. Methods A total of 88 patients with bone metastasis of lung cancer were enrolled in this study. The patients in the reference group were treated with pamidronate for injection and the study group were treated with zoledronic acid for injection. Results The pain relief, general condition and quality of life scores of the study group were significantly better than those of the reference group (P <0.05). There was no significant difference in adverse reactions between the two groups (P> 0.05). Conclusion In patients with bone metastasis of lung cancer, injection of zoledronic acid can effectively relieve pain symptoms and is safe.