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近五年来,肿瘤疾病的免疫诊断及免疫治疗处于一个崭新的领域。1975年K(?)hler及Milstein首次建立高特异性单克隆抗体,证实在肿瘤细胞内及表面有高特异性的抗原决定簇。免疫诊断抗原决定簇可用于肿瘤疾病的免疫诊断,在组织学标本、血清和体内识别最小的肿瘤残余,特别是淋巴细胞亚群的特征。免疫组织化学用免疫组织化学的方法可能选择性的描述个别细胞的组成部分,开展超微组织及超微结构区域内重要的、新的典型形态学。细胞抗原决定簇位于细胞骨架、髓磷脂蛋白、酶、细胞外胶原膜及纤合素。目前抗原虽可
In the past five years, immunological diagnosis and immunotherapy of oncological diseases are in a completely new field. In 1975 K (?) Hler and Milstein for the first time to establish high-specific monoclonal antibodies, confirmed in tumor cells and surface antigen-specific high specificity. Immunodiagnostic epitopes are useful for immunodiagnosis of oncological diseases, identifying histological specimens, sera and in vivo characteristics of minimal tumor remnants, particularly lymphocyte subsets. Immunohistochemistry With immunohistochemistry, it is possible to selectively describe individual cell components and to develop important and novel typical morphologies within the ultrastructure and ultrastructure area. Cellular epitopes are located in the cytoskeleton, myelin, enzymes, extracellular collagen membranes and fibronectin. Although the antigen can be