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本文对正常人、单纯肥胖和柯兴氏病人经蝶手术前后进行胰岛素低血糖试验,同时测定血清N-PO-MC和F的反应,结果表明正常人和单纯肥胖者血清N-POMC和F对低血糖有明显的增加反应,N-P-OMC峰在30～60分钟内出现,较基础值增加75～334％,120分钟几乎恢复到基础水平。F峰晚于N-POMC峰。相反,未治疗柯兴氏病人血清N-POMC和F对低血糖呈低下或无反应,个别病人呈减少反应,
In this paper, the insulin hypoglycemia test was performed before and after transsphenoidal surgery in normal subjects, simple obesity patients and Cushing’s patients. The response of serum N-PO-MC and F was also measured. The results showed that serum N-POMC and F in normal subjects and simple obesity patients Hypoglycemia increased significantly, NP-OMC peak appeared within 30-60 minutes, increased by 75-344% compared with the baseline, and almost recovered to basal level after 120 minutes. F peak is later than N-POMC peak. In contrast, N-POMC and F in untreated Cushing’s patients showed low or no response to hypoglycaemia, with individual patients showing a reduced response,