目的探讨残留溶剂二甲苯的测定用对照品对测定结果的影响。方法使用二甲苯中4个组分各自的对照品对5个二甲苯样品进行测定。结果 5个二甲苯样品中的4个组分的比例(乙基苯、对二甲苯、间二甲苯和邻二甲苯)是不同的,用4个组分的对照品分别计算二甲苯得到不同的含量结果。结论使用二甲苯作对照品测定溶剂残留量可能存在偏差。 OBJECTIVE To investigate the effect of reference substance for the determination of xylene in residual solvent on the determination results. Methods Five xylene samples were assayed using each of the four components in xylene. Results The proportions of the four components in the five xylene samples (ethylbenzene, para-xylene, meta-xylene and ortho-xylene) were different. Comparisons of the xylenes calculated for the four components of the control yielded different Content results. Conclusion There may be deviations in the determination of solvent residues using xylene as reference substance.