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近年来,宫内感染造成的严重后果已引起了人们的普遍关注.1964年在美国的风疹大流行中,全国因先天性风疹造成的残缺儿童达二万名.Siegal(1976)统计了妊娠早期感染风疹的孕妇333例,其中75%未完成妊娠,213例(64%)作了人工流产术,其余120例中有38例(32%)自然流产.英国在非流行时期,每年发生新生儿先天性风疹200～300例,巨细胞病毒感染400～800例,弓形体病70例,先天性梅毒30～40例,这些数据仅包括出生时已有明显临床症状者.然而,很多先天感染的婴儿于出生时常无症状,而在数年后出现症状.所以宫内感染对后代的影响是十分严重的.
In recent years, the serious consequences caused by intrauterine infection have aroused widespread concern in the United States in 1964, the rubella pandemic, due to congenital rubella caused by incomplete children up to 20,000. Siegal (1976) statistics of early pregnancy Thirty-three pregnant women infected with rubella, of whom 75% did not complete the pregnancy, 213 (64%) were abortions and the remaining 120 (38%) spontaneous abortion. Congenital rubella 200 to 300 cases, cytomegalovirus infection 400 to 800 cases, toxoplasmosis 70 cases, congenital syphilis 30 to 40 cases, these data include only those who have had significant clinical manifestations at birth However, many of the congenital infections Babies are often asymptomatic at birth and develop symptoms after years, so the impact of intrauterine infection on future generations is very serious.