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[目的]了解泉州新生儿脐血麻疹抗体水平状况,探讨制定防控措施,为降低小月龄麻疹发病提供依据。[方法]采集2008年5～8月市、乡级产科医院新生儿脐带血血清用间接ELISA法检测麻疹IgG抗体水平。[结果]2008年监测正常分娩的新生儿脐带血以≥1∶200为判定标准,抗体阳性率97.0%;以≥1∶800为判定标准,抗体保护率90.4%,平均抗体滴度(GMT)1∶3020.65。麻疹发病组的GMT倒数为5877.60(95%CI=4450.41～7762.47),均远高于接种、无接种且无发病史组。[结论]通过加强育龄妇女和新生儿麻疹抗体水平监测,开展育龄妇女疫苗加强免疫,可控制小月龄婴儿发病。
[Objective] To understand the status of umbilical cord blood measles antibody in Quanzhou and to develop prevention and control measures to provide basis for reducing the incidence of measles. [Method] The umbilical cord blood serum of newborns from municipal and township obstetrics and gynecology hospitals from May to August in 2008 was collected to detect the level of measles IgG antibody by indirect ELISA. [Results] The neonatal umbilical cord blood that monitored normal delivery in 2008 was judged as ≥1: 200, and the positive rate of antibody was 97.0%. The antibody protection rate was 90.4% and the average antibody titer (GMT) 1:3020.65. Measles morbidity group GMT countdown was 5877.60 (95% CI = 4450.41 ~ 7762.47), were much higher than the vaccination, no vaccination and no history of history. [Conclusion] By strengthening the monitoring of antibody level of measles in women of childbearing age and newborn, the vaccination of women of childbearing age to strengthen immunity can control the incidence of infant in young age.