观察双室同步起搏治疗慢性充血性心力衰竭 (CHF)的疗效及同步化治疗后尿儿茶酚胺代谢产物浓度的变化。 8例患者为扩张型或缺血性心肌病 ,符合双室同步起搏治疗的指征。治疗前及治疗后1,3 ,6月尿液儿茶酚胺代谢产物分别为 18.2± 6.1,16.4± 5 .6,15 .2± 4.3 ,14 .8± 5 .2ng/dL ;且左室舒张末期内径、左室射血分数、心功能均有改善。结论 :CHF患者双室同步起搏治疗后 ,随心功能改善 ,其神经内分泌激活程度亦可能减弱。 To observe the curative effect of biventricular synchronized pacing in patients with chronic congestive heart failure (CHF) and the change of urinary catecholamine metabolite concentration after synchronized treatment. 8 patients were dilated or ischemic cardiomyopathy, in line with the indications for dual-chamber synchronized pacing therapy. The urine catecholamine metabolites before treatment and after 1,3,6 months of treatment were 18.2 ± 6.1, 16.4 ± 5 ​​.6, 15.2 ± 4.3 and 14.8 ± 5.2 ng / dL, respectively; and the left ventricular end-diastolic diameter , Left ventricular ejection fraction, cardiac function improved. Conclusions: After double-chamber synchronized pacing in patients with CHF, the cardiac function may be improved and the neuroendocrine activation may also be weakened.