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[Miller RA et al:LancetⅡ(8240):226,1981(英文)] 作者曾研制一种可与正常人体T细胞抗原起反应的鼠单克隆抗体,在皮肤T淋巴细胞瘤(CTCL)和某些T细胞白血病患者的恶性细胞中这种抗原的水平很高。本文报告一例晚期CTCL患者用抗Leu-1单克隆抗体治疗的效果。
[Miller RA et al: Lancet II (8240): 226, 1981 (English)] The authors have developed a murine monoclonal antibody that reacts with normal human T-cell antigens in the skin T-cell lymphoma (CTCL) The level of this antigen in malignant cells of patients with T-cell leukemia is high. This article reports the effectiveness of an anti-Leu-1 monoclonal antibody in patients with advanced CTCL.