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目的研究四川纳溪地区栀子的指纹图谱,并测定西红花苷和栀子苷的含量。方法采用HPLC法建立了栀子的指纹图谱并测定不同结构西红花苷和栀子苷的含量。结果各地栀子药材与对照指纹图谱的相似度分别为0.993、0.993、0.995、0.978、0.999、0.989、0.999、0.998、0.999、0.996。不同产地栀子的栀子苷含量均在2.62%以上,平均含量为3.03%。西红花总苷含量最低为1.20%,最高为2.01%,平均含量1.63%。结论各产地栀子药材表现出较高的相似度,说明纳溪地区栀子药材所含化学成分随产地的变化小;栀子苷的含量均高于国家药典1.8%的要求,符合药用标准。西红花苷-1的含量在不同产地栀子中差异较大,但其占西红花总苷的百分比比较稳定,约为65%。
Objective To study the fingerprint of gardenia in Naxi, Sichuan Province, and to determine the content of crocin and geniposide. Methods The fingerprint of gardenia was established by HPLC and the contents of crocin and geniposide in different structures were determined. Results The similarity of Gardenia herbs and control fingerprints were 0.993,0.993,0.995,0.978,0.999,0.989,0.999,0.998,0.999,0.996 respectively. Gardenia jasminoides in different areas of the content of more than 2.62%, with an average content of 3.03%. The safflower total glycoside content of the lowest 1.20%, up to 2.01%, the average content of 1.63%. Conclusion Gardenia officinalis showed high similarity in all producing areas, indicating that the chemical composition of Gardenia officinalis contained in Naxi area changed little with the producing area. The content of geniposide was higher than the 1.8% of the national pharmacopoeia, . The content of caryol-1 in different producing gardenia vary greatly, but its percentage of saffron total glycoside is relatively stable, about 65%.