目的: 观察国产尿激酶(天普乐欣)治疗急性缺血性脑卒中的疗效及安全性。方法: 对45 例急性缺血性脑卒中患者进行临床观察。结果: 溶栓治疗后显效者11 例(25% ), 即肌力改善≥2 级, 同时伴肢体活动、言语功能及面瘫、舌瘫改善, 其余(66.6% )都有不同程度改善, 未见严重不良反应。结论: 小剂量短程溶栓疗法是治疗急性缺血性脑卒中确实有效的措施; 溶栓治疗效果与缺血性脑卒中发病时间密切相关, 强调早期诊断, 早期治疗 Objective: To observe the efficacy and safety of domestic urokinase (Tian Pu Le Xin) in the treatment of acute ischemic stroke. Methods: 45 cases of acute ischemic stroke patients were observed. Results: After thrombolytic therapy, 11 cases (25%) were markedly improved, that is, the improvement of muscle strength was ≥2 grade. Accompanied by physical activity, verbal function and facial paralysis, tongue deformity was improved, while the rest (66.6%) were improved to some extent. Serious adverse reactions. Conclusion: The short-dose, short-course thrombolytic therapy is effective in treating acute ischemic stroke. The effect of thrombolytic therapy is closely related to the onset of ischemic stroke, emphasizing early diagnosis and early treatment