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本文报道联合应用顺铀和重组人白细胞介素Ⅱ(rlL—Ⅱ)胸腔内注射治疗17例恶性肿瘤合并恶性胸水的疗效。17例患者中肺癌7例,乳腺癌6例,结肠癌、卵巢癌各2例。结果近期效果满意。总有效率(CR+PR)82.4%(14/17),其中完全缓解(CR)6例,部分缓解(PR)8例。顺铂与rlL—Ⅱ联合应用表现出明显的协同作用。
This article reported the combined use of uranyl and recombinant human interleukin II (rlL-II) intrapleural injection for the treatment of malignant tumors with malignant pleural effusion. Among the 17 patients, 7 were lung cancer, 6 breast cancer, 2 colon cancer and 2 ovarian cancer. The results were satisfactory in the near future. The total effective rate (CR+PR) was 82.4% (14/17), including 6 cases of complete remission (CR) and 8 cases of partial remission (PR). The combined use of cisplatin and rlL-II showed a clear synergistic effect.