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目的:探讨干扰素治疗水痘的效果。方法:将151例水痘患者随机分为3组,治疗组Ⅰ给予干扰素100万U/次,im,隔日1次,连用3次,治疗组Ⅱ同时予以干扰素局部外涂于水痘处,2次/d;对照组病毒唑10 mg/(kg.d),im,一日2次,连用5天。除以上治疗外,3组均同时根据病情给予退热、止痒、抗炎等对症治疗。观察3组患者症状、体征变化。结果:治疗组患者症状、体征恢复所用时间明显优于对照组,同时还发现局部外涂干扰素于水痘处,其皮疹瘙痒、结痂恢复天数明显缩短。结论:干扰素治疗水痘可减轻症状,缩短病程,配合局部外用效果更佳。
Objective: To investigate the effect of interferon on chickenpox. Methods: One hundred and fifteen patients with chickenpox were randomly divided into three groups. The treatment group Ⅰ received interferon 1 million U / time, im every other day for 3 consecutive times. In the treatment group Ⅱ, the interferon was topically applied to the chicken pox at 2 Times / d; control group ribavirin 10 mg / (kg.d), im, 2 times a day, once every 5 days. In addition to the above treatment, the three groups are given at the same time according to the disease fever, itching, anti-inflammatory symptomatic treatment. The symptoms and signs of 3 groups were observed. Results: The symptoms and signs of the patients in the treatment group were significantly better than those of the control group in the recovery of symptoms and signs. The local application of interferon in chicken pox at the same time significantly shortened the days of pruritus and scab. Conclusion: Interferon treatment of chicken pox can relieve symptoms, shorten the course of the disease, with topical effect better.