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自从Harman提出的自由基可引起细胞损伤的观点在生物学领域得到认可后,自由基在脑缺血中的作用引起了广泛重视,使缺血性脑组织损伤机制的研究从分子水平进入了亚分子水平。自1994年以来,作者通过应用通脑灵合剂治疗脑梗塞急性期患者,发现其有显著的临床效果,总有效率达94.7％,与西药对照组相比,有显著的拮抗超氧阴离子产生及提高机体超氧化物歧化酶清除自由基的作用,现小结如下。1 一般资料1.1 病例选择 均为本校一附院急诊病房住院、经头颅CT确诊为脑梗塞、发病时间小于3天的急性期患者,随机分为治
Since the idea that the free radicals proposed by Harman can cause cell damage has been recognized in the biological field, the role of free radicals in cerebral ischemia has attracted wide attention, and the mechanism of ischemic brain tissue damage has been studied from the molecular level to the Asian level. Molecular level. Since 1994, the authors have used Tongnaoling Mixture to treat patients with acute cerebral infarction and found that they have significant clinical effects, and the total effective rate is 94.7%. Compared with the western medicine control group, there is significant antagonistic production of superoxide anion and The role of superoxide dismutase scavenging of free radicals in the body is summarized below. 1 General Information 1.1 Case Selection All patients were hospitalized in the emergency room of the Affiliated Hospital of our school, and were diagnosed with cerebral infarction by head CT. Patients with acute cerebral infarction that had onset time of less than 3 days were randomized to treatment.