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患者,男,80岁。反复咳嗽,咯痰,气喘5年,再发1周,于2005年10月29日入院。体检:BP 130／80 mmHg,P 70次·min~(-1),轻度贫血貌,全身浅表淋巴结不大。桶状胸,两肺呼吸音低。未闻及干湿啰音,肝脾肋下未及,双下肢不肿。入院后实验室常规检查:RBC 2．35×10~(12)·L~(-1),Hb 77．5 g·L~(-1),Plt 21．0×10~9·L~(-1),BUN 10．8 mmol·L~(-1),Cr 207．5μmol·L~(-1)。患者3年前患前列腺癌,经去势手术后予以氟他胺等治疗,1年前发现有骨转移。本次入院后第4天,因骨疼痛经会诊后给予唑来膦酸4 mg稀释于5％葡萄糖注射液100 ml中静脉滴注治疗,滴速30滴·min~(-1)。用药6 h后患者
Patient, male, 80 years old. Repeated cough, expectoration, asthma 5 years, another 1 week, on October 29, 2005 admission. Physical examination: BP 130/80 mmHg, P 70 times · min ~ (-1), mild anemia appearance, systemic superficial lymph nodes is not large. Barrel chest, lungs breath sounds low. Unheard and wet and dry rales, liver and spleen ribs, and the lower extremity is not swollen. RBC 2.35 × 10 ~ (12) · L ~ (-1), Hb 77.5 g · L -1, Plt 21.0 × 10 ~ 9 · L ~ (-1) -1), BUN 10.8 mmol·L -1, Cr 207.5 μmol·L -1. The patient had prostate cancer three years ago and was treated with flutamide after castration surgery. One year ago, bone metastases were found. On the fourth day after the admission, 4 mg of zoledronic acid was diluted in 100 ml of 5% dextrose injection for 30 drops · min ~ (-1) after the diagnosis of bone pain. Patients after 6 h medication