作者对John Hopkins医院1925—1967年期间的成人急性横贯性脊髓病34例进行了随访研究。本组病者女性19例,男性15例,发病年龄15—55岁,2/3在青壮年,病前身体健康,无神经系统疾患,病情急性发展,原因未明,仅12例病前有一次类似病毒感染。无季节选择性。临床表现为双下肢或四肢瘫痪或无力,感觉障碍水平在颈段者4例、胸段者29例、腰段1例,其中10例后柱感觉功能保存。部份病例小便潴留。脑脊液细胞数增高者占半数,蛋白增高占1/3。从神经系统症状出现到极期时间在1小时内到14天,15例24小时内达极期。13例死亡:5例死于病后4个月内(均进行了尸检),死亡原 The authors followed 34 patients with adult acute transverse myelopathy at John Hopkins Hospital from 1925 to 1967. The group of patients 19 were females, 15 males, the age of onset 15-55 years old, 2/3 in young adults, pre-sickness, no neurological disorders, acute progression, the reason is unknown, only 12 cases before the disease once Similar virus infection. No seasonality. Clinical manifestations of both lower extremities or limbs paralysis or weakness, sensory disturbance in the neck in 4 cases, 29 cases of thoracic, lumbar in 1 case, of which 10 cases post-column preservation of sensory function. Some cases of urinary retention. Half of cerebrospinal fluid cells increased, protein increased accounted for 1/3. From neurological symptoms to the extreme period of time within 1 hour to 14 days, 15 cases reached the extreme within 24 hours. Thirteen deaths: Five died within 4 months of illness (all underwent an autopsy) and died