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目的探讨左半结肠癌并急性肠梗阻Ⅰ期切除术后发生吻合口瘘的危险因素。方法回顾性分析263例行左半结肠癌并急性肠梗阻Ⅰ期切除术患者的临床资料。结果术后发生吻合口瘘35例,发生率13.3%;合并糖尿病、术前血清白蛋白水平<30g/L、术中未充分结肠灌洗、肿瘤Dukes分期C期和D期、肿瘤直径>5cm是术后吻合口瘘发生的危险因素(P<0.05)。结论晚期左半结肠癌肿瘤体积大、合并糖尿病或低蛋白血症者易并发术后吻合口瘘,术中充分结肠灌洗可预防吻合口瘘发生。
Objective To investigate the risk factors of anastomotic fistula after Ⅰ resection of left colon cancer with acute intestinal obstruction. Methods The clinical data of 263 patients with left colon cancer who underwent primary resection of acute intestinal obstruction were retrospectively analyzed. Results 35 cases of anastomotic fistula occurred after operation, the incidence rate was 13.3%. In patients with diabetes mellitus, preoperative serum albumin level was less than 30g / L, intraoperative lavage of colonic lavage, stage C and D of tumor Dukes stage, tumor diameter> 5cm Is an important risk factor for postoperative anastomotic leakage (P <0.05). Conclusions The late stage of the left half of the colon cancer tumor volume, complicated by diabetes or hypoproteinemia are complicated by postoperative anastomotic leakage, full colon irrigation during surgery can prevent the occurrence of anastomotic leakage.