目的减少全胃切除术后食管空肠吻合口并发症，提高生存质量。方法常规全胃切除并行淋巴结廓清术，食管粘膜延长３～４ｃｍ，与空肠吻合，包埋后食管粘膜自身折叠形成乳头状置入肠腔内，起瓣膜作用。结果接受治疗的患者５８例，恢复顺利，无返流性食管炎、贫血表现，餐中、餐后无不适。结论食管粘膜与空肠乳头状吻合术，可有效地防止全胃切除术后并发症。 Objective To reduce the complications of esophagojejunostomy following total gastrectomy and improve the quality of life. Methods Routine total gastrectomy with lymphadenectomy, esophageal mucosa was extended 3 ~ 4cm, anastomosis with the jejunum, esophageal mucosa after self-folding to form a papillary shape into the intestinal lumen, play a valve role. Results Of the 58 patients who were treated, they recovered smoothly without reflux esophagitis, anemia, and no discomfort during meals and after meals. Conclusion Esophageal mucosa and jejunal papillary anastomosis can effectively prevent complications after total gastrectomy.