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地塞米松(Dex)抑制性高醛固酮血症(DSH)是伴有高血压、高醛固酮血症、低肾素血症、低钾血症等皮质腺瘤引起的与原发性高醛固酮症(APA)类似症状的疾病,特征是投给小剂量(0.5～1.5mg/d)Dex1周～2周,可改善上述症状;此外血中皮质醇动态正常,但连续数日投给ACTH时,则与健康人或APA不同,醛固酮分泌持续上升等。本病病因、病理尚不完全清楚。如(1)本病醛固酮分泌是否有ACTH依赖性;(2)本病醛固酮分泌是来自肾上腺球状带还是束状带;(3)本病之高血压是否与未知的电解质类固醇有关等。 1968年日本Miura等报告了第1例类似本病病
Dexed inhibited aldosteronism (DSH) is associated with high aldosteronism (hypertension) caused by cortical adenomas such as hypertension, hyperaldosteronism, hypoxemia, hypokalemia APA) symptoms characterized by small doses (0.5 ~ 1.5mg / d) Dex1 weeks ~ 2 weeks, can improve the above symptoms; In addition, blood cortisol normal, but after a few days for ACTH, then Unlike healthy people or APA, aldosterone secretion continued to rise. The etiology of the disease, the pathology is not yet fully understood. Such as (1) whether the disease aldosterone secretion ACTH-dependent; (2) the disease aldosterone secretion from the adrenal globular or fascicular band; (3) the disease is not related to the unknown electrolyte steroid-related. In 1968 Japan Miura et al reported the first case similar to the disease