论文部分内容阅读
目的:描述阻塞性睡眠呼吸暂停低通气综合征(OSAS)合并高血压患者中,原发性醛固酮增多症(PA)按血压分类的筛查情况。方法:回顾性分析新疆自治区人民医院高血压诊疗中心337例确诊为OSAS合并高血压的患者,在标化状态下以坐位血浆醛固酮/肾素比值≥25为PA的筛查标准。结果:①OSAS合并单纯收缩期高血压中PA筛出4例,初筛率是21.05%;OSAS合并单纯舒张期高血压中PA筛出9例,初筛率是12.68%;OSAS合并二者均高的高血压中PA筛出29例,初筛率是16.48%。但不同亚组间PA初筛率无显著差异。②OSAS合并1级高血压中筛出18例PA,初筛率是15%;OSAS合并2级高血压中筛出18例PA,初筛率是18.75%;OSAS合并3级高血压中筛出6例PA,初筛率是12%。但不同级别间PA初筛率无显著差异。结论:在OSAS合并高血压患者中,按血压分类的PA初筛率没有不同。
Objective: To describe the screening of primary aldosteronism (PA) according to blood pressure classification in patients with obstructive sleep apnea-hypopnea syndrome (OSAS) and hypertension. Methods: 337 patients diagnosed as OSAS complicated with hypertension were retrospectively analyzed. According to the standard of screening, the plasma aldosterone / renin ratio ≥25 was used as the screening standard of PA in the sitting position. Results: ①OSAS with isolated systolic hypertension in 4 cases of PA screening, the first screening rate was 21.05%; OSAS with simple diastolic hypertension in PA screening out 9 cases, the screening rate was 12.68%; OSAS were both high Of the 29 patients with hypertension in PA screening, the primary screening rate was 16.48%. However, there was no significant difference in the rate of PA screening among different subgroups. ②OSAS combined with grade 1 hypertension in 18 cases of screening out of PA, the screening rate was 15%; OSAS combined with 2 levels of hypertension in 18 cases of screening out of PA, the screening rate was 18.75%; OSAS with hypertension in the screening out of 6 Example PA, the initial screening rate was 12%. However, there was no significant difference in the rate of PA screening between different grades. CONCLUSIONS: There is no difference in the rate of PA screening by blood pressure among OSAS patients with hypertension.