论文部分内容阅读
A 45-year-old male cook was seen for the evaluation and removal of a “mole o n my eye” of steady growth during the previous 6 months. The patient stated that he had had a “brown spot” above his left eye for 17 years prior to its recent e nlargement; it was now partly blocking the vision in his left eye. He denied a h istory or family history of cutaneous tumors, including skin cancer. On examinat ion, a 2.5-cm ×.0.5-cm ×.0.8-cm, horn-like, darkly pigmented, cutaneous no dule was evident extending from the left upper eyelid downwards to below the low er eyelid (Figs 1 and 2). He also had scattered, skin-colored, 2-3-mm cystic papules on his anterior mid-chest. A shave excision specimen was obtained from the eyelid nodule. Microscopic examination demonstrated acanthosis, hyperkeratos is, and papillomatosis (Fig. 3). Large dendritic cells with abundant melanin gra nules were spread throughout the epidermis. In addition, small basaloid or spino us keratinocytes were present in the malpighian layer.
A 45-year-old male was was for the evaluation and removal of a “mole on my eye” of steady growth during the previous 6 months. The patient stated that he had had a “brown spot” above his his left eye for 17 years prior to its recent e nlargement; it was now partly blocked the vision in his left eye. He denied ah istory or family history of cutaneous tumors, including skin cancer. On examinat ion, a 2.5-cm × .0.5 -cm × .0.8-cm, horn-like, darkly pigmented, cutaneous no dule was showed extending from the left upper eyelid downwards to below the low er eelide (Figs 1 and 2). He also had scattered, skin-colored, 2 -3-mm cystic papules on his anterior mid-chest. A shave excision specimen was obtained from the eyelid nodule. Microscopic examination demonstrated acanthosis, hyperkeratos is, and papillomatosis (Fig. 3). Large dendritic cells with abundant melanin gra nules were spread throughout the epidermis. In addition, small basaloid or spino us keratinocytes were present in the ma lpighian layer.