这是一个以大量蛋白尿、低蛋白血症、水肿和高胆固醇血症为其特征的临床综合症。病程中有时可发生高血压、氮质血症、低丙种球蛋白血症和血尿。近年来动物试验证明肾病可由身体免疫引起。肾病组织学改变,近年来有了很大进展。1970年由Churg氏分为四组: 1.微小病变型(Minimal changes) 在光学显微镜下示肾小球正常或细胞有轻微增加,血管间质中没有类基底膜样纤维沉淀物。电子显微镜下可见上皮细胞足突滆 This is a clinical syndrome characterized by massive proteinuria, hypoproteinemia, edema and hypercholesterolemia. Hypertension, azotemia, hypogammaglobulinemia and hematuria sometimes occur during the course of the disease. In recent years, animal experiments show that kidney disease can be caused by body immunity. Nephrology histological changes in recent years have made great progress. 1970 Churg divided into four groups: 1. Minimal changes under the optical microscope glomerular normal or a slight increase in cells, there is no basement membrane-like fiber deposits in the vascular stroma. Epithelial cells were found under electron microscopy