作者研究了一例早期膀胱癌,其绝大多数中期分裂相改变仅是5q缺失。标本来源于一名近期有血尿的78岁男患,从其膀胱中切除了一个有绒毛表面的带蒂肿瘤,镜检表明是仅侵犯粘膜的Ⅱ度乳头状间变细胞癌。取肿瘤的一部分直接进行染色体研究,总共计数了40个分裂相,36个有46条染色体,1个有47条染色体,3个染色体数为亚二倍体, The authors studied an early case of bladder cancer whose vast majority of metaphase changes were only 5q deletions. Specimens from a recent 78-year-old man with hematuria, from its bladder removed a villous surface of the pedunculated tumor, microscopic examination showed only invasive mucosal Ⅱ degree papillary change. A portion of the tumor was directly studied for chromosomes, counting a total of 40 split phases, 36 with 46 chromosomes, one with 47 chromosomes, three with sub-diploid chromosomes,