细胞因子是宿主抵御微生物包括衣原体感染的主要组成部分。近来发现它们可能会干扰衣原体在细胞内的正常生长,从而导致衣原体持续感染,作为抗原慢性刺激,最终参与衣原体疾病的免疫致病机理。如通过细胞培养系统,发现高浓度γ干扰素(IFN-γ)可完全抑制衣原体生长,而中、低浓度则使衣原体超微结构表现为 Cytokines are a major component of a host’s defense against microorganisms, including chlamydial infections. It has recently been found that they may interfere with the normal growth of Chlamydia in the cell, resulting in persistent infection of Chlamydia, as a chronic stimulation of antigen, eventually involved in the pathogenesis of Chlamydia. As demonstrated by the cell culture system, high concentrations of interferon-gamma (IFN-γ) were found to completely inhibit the growth of Chlamydia, whereas the medium and low concentrations of Chlamydomonas reinhardtii