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目的 评价前程加速放射治疗食管癌的疗效。方法 自 1994年 1月至 1996年 2月 ,选择 10 6例食管癌患者 ,随机分为两组 :(1)前程加速放射治疗组 5 3例 ,放射治疗第 1,2周 ,每天 3Gy ,5次 /周 ,第 3 ,4周 ,每天 2Gy ,5次 /周 ,总剂量 5 0Gy/ 4周 ;(2 )常规放射治疗组 5 3例 ,每天 2Gy ,5次 /周 ,总剂量 60Gy/ 6周。 结果 前程加速组 5年局部控制率和 5年生存率明显高于常规放疗组 ,分别为 41.5 %比 18.9%和 18.7%比 9.7% ,放疗副作用两组无明显差别。结论 结果显示前程加速放射治疗能提高食管癌局部控制率和生存率。
Objective To evaluate the effect of accelerated radiotherapy on esophageal cancer. Methods From January 1994 to February 1996, 106 patients with esophageal cancer were selected and randomly divided into two groups: (1) 53 cases of accelerated radiotherapy group, 1 week and 2 weeks of radiotherapy, 3Gy, 5 The total dose of 5 Gy / 4 weeks, 2Gy, 5 times / week, 5 Gy / 4 weeks, week. Results The 5-year local control rate and 5-year survival rate in the accelerated group were significantly higher than those in the conventional radiotherapy group (41.5% vs 18.9% vs 18.7% vs 9.7%, respectively). There was no significant difference between the two groups in radiotherapy side effects. Conclusion The results show that accelerated accelerated radiation therapy can improve the local control of esophageal cancer and survival rate.