论文部分内容阅读
本文报导2例增殖性脓性口炎患者。例1,23岁女性。1976年开始下腹部间歇性痛性痉挛,交替发作便秘和腹泻,大便带血和粘液。经大便检查,直肠镜及结肠镜检查,钡灌肠及肝活检,确诊为慢性溃疡性结肠炎和胆管周围炎。用柳氮磺胺吡啶(500mg,日3次)和强的松(30mg,日3次)治疗,腹泻和血便消失。当药物减量时,腹泻又发。1978年6月全口粘膜及气管和喉发生痛性溃疡,声音嘶哑。损害活检仅显示粘膜坏死,直接免疫荧光检查阴性。口腔局部应用四环素等几乎无效。1979年8月因柳氮磺胺吡啶引起苔藓样药物反应而停此药。1980年7月在
This article reports 2 cases of proliferative purulent stomatitis patients. Example 1,23-year-old woman. Beginning in 1976, the lower abdomen intermittent painful cramps, alternating episodes of constipation and diarrhea, stool bloody and mucus. After the stool examination, colonoscopy and colonoscopy, barium enema and liver biopsy, diagnosed as chronic ulcerative colitis and peribiliary inflammation. Diarrhea and bloody stool disappeared with sulfasalazine (500 mg three times daily) and prednisone (30 mg three times daily). When the medicine is reduced, the diarrhea sends again. June 1978 full mouth mucous membrane and tracheal and throat painful ulcer, hoarseness. Damage biopsy showed only mucosal necrosis, direct immunofluorescence negative. Oral topical tetracycline, etc. almost ineffective. August 1979 Sulfasalazine caused by mosquito drug response and stop the drug. July 1980