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目的探讨经颅高频超声在高危新生儿室管膜下区病变诊断中的价值。方法对730例高危新生儿进行经颅脑高频超声检查,对图像进行分析。结果 730例新生儿中,61例室管膜下病变,18例单纯性室管膜下囊肿(SEC),43例室管膜下出血(SEH)。441例早产儿(<37周)中SEH患儿33例(33/441,7.48%);289例足月儿(≥37周)中SEH患儿10例(10/289,3.46%),两者SEH发生率比较差异有统计学意义(χ~2=5.097,P<0.05)。403例低体重儿(<2500 g)中SEH患儿35例(35/403,8.68%);327例正常体重儿(≥2500 g)中SEH患儿8例(8/327,2.45%),两者SEH发生率比较差异有统计学意义(χ~2=12.67,P<0.01)。结论胎龄越小、出生体重越低,室管膜下出血发生率越高;经颅高频超声可以针对性的观察高危新生儿室管膜下病变变化情况,有利于动态随访观察颅脑疾病的变化,指导临床治疗。
Objective To investigate the value of transcranial high frequency ultrasonography in the diagnosis of subependymal lesions in high-risk neonates. Methods 730 cases of high-risk newborns were examined by high-frequency ultrasound brain, the image analysis. Results Of the 730 newborns, 61 had subependymal lesions, 18 had simple subependycosis (SEC), and 43 had subependymal hemorrhage (SEH). Among 441 preterm infants (<37 weeks), 33 cases (33 / 441,7.48%) had SEH and 10 (289 cases, 3.46%) had SEH in 289 infants (≥37 weeks) The incidence of SEH was significantly different (χ ~ 2 = 5.097, P <0.05). 35 cases (35/403, 8.68%) had SEH in 403 cases of low birth weight infants (<2500 g), 8 cases (8 / 327,2.45%) of SEH children in 327 cases of normal weight (≥2500 g) The incidence of SEH between the two groups was statistically significant (χ ~ 2 = 12.67, P <0.01). Conclusions The smaller the gestational age, the lower the birth weight, the higher the incidence of subependymal hemorrhage. The transcranial high-frequency ultrasound can be used to observe the changes of subependymal lesions in high-risk neonates, which is conducive to dynamic follow-up observation of craniocerebral diseases Change, guide clinical treatment.