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目的:探讨复方米非司酮用于药物流产的效果。方法:因非意愿妊娠要求行药物流产者随机分为3组,A组:口服复方米非司酮(米非司酮30 mg+双炔失碳酯5 mg),1片/d,qd×2 d,第3日口服米索前列醇0.6 mg;B组:服米非司酮(25 mg/片)1片,bid×3 d,第4日口服米索前列醇0.6 mg;C组:口服米非司酮2片,qd×3 d,第4日口服米索前列醇0.6 mg。结果:A组完全流产率高于B组和C组,孕囊排出时间和完全流产者出血时间A组较B组、C组缩短,差异均有统计学意义(P<0.05)。结论:复方米非司酮用于药物流产成功率高,出血时间短,值得临床广泛使用。
Objective: To investigate the effect of compound mifepristone on medical abortion. Methods: The abortion patients were randomly divided into three groups according to the unplanned pregnancy. Group A: Oral mifepristone (mifepristone 30 mg + anordrin 5 mg), 1 tablet / d, qd × 2 d, oral misoprostol 0.6 mg on day 3; group B: 1 tablet of mifepristone (25 mg / tablet), bid x 3 d, oral misoprostol 0.6 mg on day 4; Group C: oral Mifepristone 2, qd × 3 d, on the 4th oral misoprostol 0.6 mg. Results: The rate of complete abortion in group A was higher than those in groups B and C, the time of discharging in gestational sac and the bleeding time in complete abortion group were shorter than those in group B and C (P <0.05). Conclusions: The success rate of compound mifepristone for medical abortion is high, bleeding time is short, and it is worth widely used in clinic.