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[目的]分析健康体检空腹血糖受损(IFG)人群的临床特征。[方法]采用横断面分析的方法对健康体检者1198例,根据空腹血糖状态分为糖耐量正常(NGT)组、空腹血糖受损(IFG)组、糖尿病(DM)组,比较各组间临床特征。并针对IFG组在不同年龄及不同性别的临床特征进行分析。[结果]与NGT组比较,IFG人群收缩压(SBP)、舒张压(DBP)、体重指数(BMI)、甘油三酯(TG)、总胆固醇(TC)及低密度脂蛋白-胆固醇(LDL-C)明显增高;高密度脂蛋白-胆固醇(HDL-C)明显减低;血脂紊乱、高血压、肥胖/超重患病率、存在3个及以上危险因素比率明显增高。与DM组比较,IFG组SBP、DBP升高程度不如DM组显著。IFG组随着年龄增高SBP、LDL-C明显增高;老年人群较青年人群血脂紊乱及高血压患病率增高。IFG组男性在DBP、TG及肥胖/超重患病率显著高于女性。[结论]IFG时期已存在血脂代谢紊乱、肥胖/超重、血压升高趋势;IFG人群在年龄和性别上临床代谢特征不同。
[Objective] To analyze the clinical features of healthy volunteers with impaired fasting glucose (IFG). [Methods] A total of 1198 healthy subjects were divided into three groups according to the fasting blood glucose status: the normal glucose tolerance group (NGT) group, the impaired fasting glucose (IFG) group and the diabetic group (DM) feature. The clinical features of IFG group at different ages and genders were analyzed. [Results] Compared with NGT group, SBP, DBP, BMI, TG, TC and LDL- C) was significantly higher; HDL-C was significantly lower; the prevalence of dyslipidemia, hypertension and obesity / overweight were significantly higher in the presence of three or more risk factors. Compared with DM group, the level of SBP and DBP in IFG group was not as significant as DM group. In the IFG group, SBP and LDL-C increased significantly with age; the incidence of dyslipidemia and hypertension in the elderly population was higher than that in the younger population. The prevalence of DBP, TG, and obesity / overweight in men in IFG group was significantly higher than that in women. [Conclusion] The dyslipidemia, obesity / overweight and the rising of blood pressure have existed in the period of IFG. The characteristics of clinical metabolism in IFG population are different in age and sex.