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按pH梯度提取,结合柱层析,从赣皖乌头的根中分得五种结晶性的生物硷。按其理化性质及光谱数据,分别鉴定为翠雀索灵(delsoline)(Ⅰ),阿瓦乌头硷(avadharidine)(Ⅱ) ,牛扁次硷(lycoctonine)(Ⅲ)和另外二种生物硷(Ⅳ)、(Ⅴ),其实验式(熔点)分别为:C_(27)H_(21)N_3O_5(141～42℃)、C_(72)H_(31)NO_3(221～26℃),结构正在进行鉴定。(Ⅰ)可治疗急性菌痢和急性肠炎,并具有松弛肠平滑肌的作用。
According to the extraction of pH gradient and combined with column chromatography, five kinds of crystalline bio-germanium were obtained from the roots of Aconitum vulgaris. According to their physical and chemical properties and spectral data, they were identified as delsoline (I), avadidine (II), lycoctonine (III) and two other organisms. (IV), (V), its experimental formula (melting point) are: C 27 H 21 N 3 O 5 (141-42° C), C 72 H 31 N 3 (221-26° C), structure Identification is ongoing. (I) It can treat acute bacillary dysentery and acute enteritis and has the effect of relaxing intestinal smooth muscle.