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应用放射免疫分析法.检测30例间质性肺病(ILD)病例和9例正常对照者的BALF中糖胺多糖的水平;并根据ILD病程、病期及BALF中细胞成分变化进行综合分析。结果;①ILD组BALF中糖胺多糖水平明显高于正常对照组(P<0.05);②BALF中糖胺多糖水平与ILD病程或病期有关,与BALF中炎性细胞百分比呈密切正相关(P<0.05)。说明BALF中糖胺多糖水平的研究,对辅助诊断ILD、纤维化程度的判断及活动性评价等均有重要临床意义。
Application of radioimmunoassay. 30 patients with interstitial lung disease (ILD) cases and 9 normal controls BALF glycosaminoglycan levels; and ILD according to disease duration, and changes in cellular components of BALF were analyzed. Results ① The levels of glycosaminoglycans in BALF ofILD group were significantly higher than those in normal control group (P <0.05). ② The levels of glycosaminoglycan in BALF were correlated with the course of disease or stage of ILD, and positively correlated with the percentage of inflammatory cells in BALF P <0.05). Description of glycosaminoglycan in BALF levels of research, to help diagnose ILD, the degree of fibrosis to determine the degree of activity and evaluation are of important clinical significance.