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目的探讨儿童再发性呕吐临床治疗效果。方法 2008年6月至2011年6月收治的符合入选标准儿童再发性呕吐病例60例为常规组32例,治疗组28例观察两组临床疗效。结果两组临床近期疗效治疗组总有效率92.85%,常规组总有效率65.62%,经统计学分析,两组总有效率比较有显著差异性(P<0.01)。结论发病率约为儿童3.15/10万,是继胃食管反流造成儿童反复呕吐的第二病因;本病反复频繁发作,发作形式刻板,具有突发突止特性,任何年龄阶段儿童均可发病<5岁的儿童多发,无显著性别差异;典型症状为突然出现反复剧烈恶心、呕吐,发作可以持续数小时到数天,同时伴有自主神经全身症状如轻度血压增高、多汗、流涎、发热、面色苍白、嗜睡、乏力等;神经系统症状可以出现头痛、眩晕、畏声、畏光等。急性期应用胞二磷胆碱及连续应用多虑平、赛庚啶可以显著缩短儿童再发性呕吐急性发作期,减少复发。
Objective To investigate the clinical effect of recurrent vomiting in children. Methods Between June 2008 and June 2011, 60 children with recurrent vomiting who meet the inclusion criteria were treated in the conventional group of 32 cases and the treatment group of 28 cases. The clinical efficacy was observed in both groups. Results The total effective rate was 92.85% in the treatment group and 65.62% in the conventional group. The total effective rate was significantly different between the two groups (P <0.01). Conclusions The incidence rate is about 3.15 / 100000 children, which is the second cause of recurrent vomiting in children after gastroesophageal reflux. The disease frequently recurrent and episodes, the form of attack is stereotyped and has the sudden and sudden trait, which can occur in children of any age <5 years of age children with multiple sexes, no significant gender differences; typical symptoms of sudden severe repeated nausea, vomiting, seizures can last for several hours to several days, accompanied by systemic symptoms of autonomic nervous, such as mild hypertension, hyperhidrosis, salivation, Fever, pale, drowsiness, fatigue, etc .; nervous system symptoms can occur headache, dizziness, fear of sound, photophobia and so on. Application of citicoline acute phase and continuous application of doxepin, cyproheptadine can significantly shorten the acute recurrent emetic vomiting, reduce recurrence.